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Estrogen Regulates JNK1 Genomic Localization to Control Gene Expression and Cell Growth in Breast Cancer Cells

Steroid hormone and MAPK signaling pathways functionally intersect, but the molecular mechanisms of this cross talk are unclear. Here, we demonstrate a functional convergence of the estrogen and c-Jun N-terminal kinase 1 (JNK1) signaling pathways at the genomic level in breast cancer cells. We find...

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Bibliografiske detaljer
Main Authors: Sun, Miao, Isaacs, Gary D., Hah, Nasun, Heldring, Nina, Fogarty, Elizabeth A., Kraus, W. Lee
Format: Artigo
Sprog:Inglês
Udgivet: Endocrine Society 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355551/
https://ncbi.nlm.nih.gov/pubmed/22446103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1158
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