A genome-wide study reveals rare CNVs exclusive to extreme phenotypes of Alzheimer disease

Studying rare extreme forms of Alzheimer disease (AD) may prove to be a useful strategy in identifying new genes involved in monogenic determinism of AD. Amyloid precursor protein (APP), PSEN1, and PSEN2 mutations account for only 85% of autosomal dominant early-onset AD (ADEOAD) families. We hypoth...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Rovelet-Lecrux, Anne, Legallic, Solenn, Wallon, David, Flaman, Jean-Michel, Martinaud, Olivier, Bombois, Stéphanie, Rollin-Sillaire, Adeline, Michon, Agnès, Le Ber, Isabelle, Pariente, Jérémie, Puel, Michèle, Paquet, Claire, Croisile, Bernard, Thomas-Antérion, Catherine, Vercelletto, Martine, Lévy, Richard, Frébourg, Thierry, Hannequin, Didier, Campion, Dominique
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355247/
https://ncbi.nlm.nih.gov/pubmed/22166940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2011.225
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker