Angiotensin Converting Enzyme 2 Contributes to Sex Differences in the Development of Obesity Hypertension in C57BL/6 Mice

OBJECTIVE: Obesity promotes hypertension, but it is unclear if sex differences exist in obesity-related hypertension. Angiotensin converting enzyme 2 (ACE2) converts angiotensin II (AngII) to angiotensin-(1–7) (Ang-[1–7]), controlling peptide balance. We hypothesized that tissue-specific regulation...

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Hlavní autoři: Gupte, Manisha, Thatcher, Sean E., Boustany-Kari, Carine M., Shoemaker, Robin, Yiannikouris, Frederique, Zhang, Xuan, Karounos, Michael, Cassis, Lisa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355213/
https://ncbi.nlm.nih.gov/pubmed/22460555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.248559
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