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Feedback within the Inter-Cellular Communication and Tumorigenesis in Carcinomas

The classical somatic mutation theory (SMT) of carcinogenesis and metastasis postulates that malignant transformation occurs in cells that accumulate a sufficient amount of mutations in the appropriate oncogenes and/or tumor suppressor genes. These mutations result in cell-autonomous activation of t...

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Detalhes bibliográficos
Main Authors: Rückert, Felix, Grützmann, Robert, Pilarsky, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355145/
https://ncbi.nlm.nih.gov/pubmed/22615799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036719
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