Expanding the Hygiene Hypothesis: Early Exposure to Infectious Agents Predicts Delayed-Type Hypersensitivity to Candida among Children in Kilimanjaro

BACKGROUND: Multiple lines of evidence suggest that infections in early life prevent the development of pathological immune responses to allergens and autoantigens (the hygiene hypothesis). Early infections may also affect later immune responses to pathogen antigen. METHODS: To evaluate an associati...

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Autors principals: Wander, Katherine, O'Connor, Kathleen, Shell-Duncan, Bettina
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355133/
https://ncbi.nlm.nih.gov/pubmed/22616000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037406
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