Expanding the Hygiene Hypothesis: Early Exposure to Infectious Agents Predicts Delayed-Type Hypersensitivity to Candida among Children in Kilimanjaro

BACKGROUND: Multiple lines of evidence suggest that infections in early life prevent the development of pathological immune responses to allergens and autoantigens (the hygiene hypothesis). Early infections may also affect later immune responses to pathogen antigen. METHODS: To evaluate an associati...

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Библиографические подробности
Главные авторы: Wander, Katherine, O'Connor, Kathleen, Shell-Duncan, Bettina
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355133/
https://ncbi.nlm.nih.gov/pubmed/22616000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037406
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