UBR2 of the N-End Rule Pathway Is Required for Chromosome Stability via Histone Ubiquitylation in Spermatocytes and Somatic Cells

The N-end rule pathway is a proteolytic system in which its recognition components (N-recognins) recognize destabilizing N-terminal residues of short-lived proteins as an essential element of specific degrons, called N-degrons. The RING E3 ligases UBR2 and UBR1 are major N-recognins that share size...

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Detalhes bibliográficos
Main Authors: An, Jee Young, Kim, Euna, Zakrzewska, Adriana, Yoo, Young Dong, Jang, Jun Min, Han, Dong Hoon, Lee, Min Jae, Seo, Jai Wha, Lee, Yong Jun, Kim, Tae-You, de Rooij, Dirk G., Kim, Bo Yeon, Kwon, Yong Tae
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355131/
https://ncbi.nlm.nih.gov/pubmed/22616001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037414
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