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Drosophila Activated Cdc42 Kinase Has an Anti-Apoptotic Function

Activated Cdc42 kinases (Acks) are evolutionarily conserved non-receptor tyrosine kinases. Activating somatic mutations and increased ACK1 protein levels have been found in many types of human cancers and correlate with a poor prognosis. ACK1 is activated by epidermal growth factor (EGF) receptor si...

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書誌詳細
主要な著者: Schoenherr, Jessica A., Drennan, J. Michelle, Martinez, Juan S., Chikka, Madhusudana Rao, Hall, Mark C., Chang, Henry C., Clemens, James C.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355085/
https://ncbi.nlm.nih.gov/pubmed/22615583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002725
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