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Drosophila Activated Cdc42 Kinase Has an Anti-Apoptotic Function
Activated Cdc42 kinases (Acks) are evolutionarily conserved non-receptor tyrosine kinases. Activating somatic mutations and increased ACK1 protein levels have been found in many types of human cancers and correlate with a poor prognosis. ACK1 is activated by epidermal growth factor (EGF) receptor si...
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| Autori principali: | , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355085/ https://ncbi.nlm.nih.gov/pubmed/22615583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002725 |
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