Insufficient maintenance DNA methylation is associated with abnormal embryonic development

BACKGROUND: Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function...

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Dades bibliogràfiques
Autors principals: Yin, Li-Jun, Zhang, Yu, Lv, Ping-Ping, He, Wei-Hua, Wu, Yan-Ting, Liu, Ai-Xia, Ding, Guo-Lian, Dong, Min-Yue, Qu, Fan, Xu, Chen-Ming, Zhu, Xiao-Ming, Huang, He-Feng
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355050/
https://ncbi.nlm.nih.gov/pubmed/22413869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-26
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