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Insufficient maintenance DNA methylation is associated with abnormal embryonic development

BACKGROUND: Early pregnancy loss (EPL) is a frustrating clinical problem, whose mechanisms are not completely understood. DNA methylation, which includes maintenance methylation and de novo methylation directed by DNA methyltransferases (DNMTs), is important for embryo development. Abnormal function...

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Detalhes bibliográficos
Main Authors: Yin, Li-Jun, Zhang, Yu, Lv, Ping-Ping, He, Wei-Hua, Wu, Yan-Ting, Liu, Ai-Xia, Ding, Guo-Lian, Dong, Min-Yue, Qu, Fan, Xu, Chen-Ming, Zhu, Xiao-Ming, Huang, He-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3355050/
https://ncbi.nlm.nih.gov/pubmed/22413869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-10-26
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