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Structural basis of substrate specificity of bifunctional isocitrate dehydrogenase kinase/phosphatase
Isocitrate dehydrogenase kinase/phosphatase (AceK) regulates entry into the glyoxylate bypass by reversibly phosphorylating isocitrate dehydrogenase (ICDH). Based on the recent complex structure of AceK-ICDH from E. coli, we have classified the structures of homodimeric NADP(+)-ICDHs to rationalize...
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| Main Authors: | , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354702/ https://ncbi.nlm.nih.gov/pubmed/21870819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi200809p |
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