Suppression of tumor invasion and metastasis by concurrent inhibition of c-Met and VEGF signaling in pancreatic neuroendocrine tumors

Invasion and metastasis increase after inhibition of vascular endothelial growth factor (VEGF) signaling in some preclinical tumor models. The present study asked whether selective VEGF inhibition is sufficient to increase invasion and metastasis and whether selective c-Met inhibition is sufficient...

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Hauptverfasser: Sennino, Barbara, Ishiguro-Oonuma, Toshina, Wei, Ying, Naylor, Ryan M., Williamson, Casey W., Bhagwandin, Vikash, Tabruyn, Sebastien P., You, Weon-Kyoo, Chapman, Harold A., Christensen, James G., Aftab, Dana T., McDonald, Donald M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354652/
https://ncbi.nlm.nih.gov/pubmed/22585997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0240
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