The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma

The Cancer Genome Atlas (TCGA) project has generated gene expression data that divides glioblastoma (GBM) into four transcriptional classes: proneural, neural, classical, and mesenchymal. Because transcriptional class is only partially explained by underlying genomic alterations, we hypothesize that...

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Detalhes bibliográficos
Main Authors: Cooper, Lee A.D., Gutman, David A., Chisolm, Candace, Appin, Christina, Kong, Jun, Rong, Yuan, Kurc, Tahsin, Van Meir, Erwin G., Saltz, Joel H., Moreno, Carlos S., Brat, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2012
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354586/
https://ncbi.nlm.nih.gov/pubmed/22440258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.040
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