The Tumor Microenvironment Strongly Impacts Master Transcriptional Regulators and Gene Expression Class of Glioblastoma

The Cancer Genome Atlas (TCGA) project has generated gene expression data that divides glioblastoma (GBM) into four transcriptional classes: proneural, neural, classical, and mesenchymal. Because transcriptional class is only partially explained by underlying genomic alterations, we hypothesize that...

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Autors principals: Cooper, Lee A.D., Gutman, David A., Chisolm, Candace, Appin, Christina, Kong, Jun, Rong, Yuan, Kurc, Tahsin, Van Meir, Erwin G., Saltz, Joel H., Moreno, Carlos S., Brat, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2012
Matèries:
Regular Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354586/
https://ncbi.nlm.nih.gov/pubmed/22440258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.01.040
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