Phosphorylation of EBP50 negatively regulates β-PIX-dependent Rac1 activity in anoikis

We demonstrated a protein kinase C (PKC)-dependent phosphorylation of canine ezrin/radixin/moesin (ERM)-binding phosphoprotein 50 (EBP50) at serine 347/348 by site-directed mutagenesis and a phospho-specific antibody. Cell fractionation and confocal imaging revealed the relocation of EBP50 from the...

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Autors principals: Chen, J-Y, Lin, Y-Y, Jou, T-S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2012
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354064/
https://ncbi.nlm.nih.gov/pubmed/22301917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2012.4
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