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FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression
Forkhead transcription factors of the O class (FOXOs) are important targets of the phosphatidylinositol 3-kinase/Akt pathway, and are key regulators of the cell cycle, apoptosis and response to oxidative stress. FOXOs have been shown to have tumour suppressor function and are important for stem cell...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3354049/ https://ncbi.nlm.nih.gov/pubmed/22139133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.179 |
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