FOXO3a regulates reactive oxygen metabolism by inhibiting mitochondrial gene expression

Forkhead transcription factors of the O class (FOXOs) are important targets of the phosphatidylinositol 3-kinase/Akt pathway, and are key regulators of the cell cycle, apoptosis and response to oxidative stress. FOXOs have been shown to have tumour suppressor function and are important for stem cell...

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Bibliographic Details
Main Authors: Ferber, E C, Peck, B, Delpuech, O, Bell, G P, East, P, Schulze, A
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2012
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3354049/
https://ncbi.nlm.nih.gov/pubmed/22139133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2011.179
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