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Evolutionary Constraint Helps Unmask a Splicing Regulatory Region in BRCA1 Exon 11
BACKGROUND: Alternative splicing across exon 11 produces several BRCA1 isoforms. Their proportion varies during the cell cycle, between tissues and in cancer suggesting functional importance of BRCA1 splicing regulation around this exon. Although the regulatory elements driving exon 11 splicing have...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3353946/ https://ncbi.nlm.nih.gov/pubmed/22615956 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037255 |
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