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Coupling of Glucose Deprivation with Impaired Histone H2B Monoubiquitination in Tumors

Metabolic reprogramming is associated with tumorigenesis. However, glucose metabolism in tumors is poorly understood. Here, we report that glucose levels are significantly lower in bulk tumor specimens than those in normal tissues of the same tissue origins. We show that mono-ubiquitinated histone H...

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Detalhes bibliográficos
Main Authors: Urasaki, Yasuyo, Heath, Linda, Xu, C. Wilson
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353945/
https://ncbi.nlm.nih.gov/pubmed/22615809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036775
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