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Histone H2A and H2B Are Monoubiquitinated at AID-Targeted Loci

BACKGROUND: Somatic hypermutation introduces base substitutions into the rearranged and expressed immunoglobulin (Ig) variable regions to promote immunity. This pathway requires and is initiated by the Activation Induced Deaminase (AID) protein, which deaminates cytidine to produce uracils and UG mi...

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Detalhes bibliográficos
Main Authors: Borchert, Glen M., Holton, Nathaniel W., Edwards, Kevin A., Vogel, Laura A., Larson, Erik D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2905439/
https://ncbi.nlm.nih.gov/pubmed/20661291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011641
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