Targeting of the Human Coagulation Factor IX Gene at rDNA Locus of Human Embryonic Stem Cells

BACKGROUND: Genetic modification is a prerequisite to realizing the full potential of human embryonic stem cells (hESCs) in human genetic research and regenerative medicine. Unfortunately, the random integration methods that have been the primary techniques used keep creating problems, and the prima...

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Detalhes bibliográficos
Main Authors: Liu, Xionghao, Wu, Yong, Li, Zhuo, Yang, Junlin, Xue, Jinfeng, Hu, Youjin, Feng, Mai, Niu, Wenbin, Yang, Qiurui, Lei, Ming, Xia, Jiahui, Wu, Lingqian, Liang, Desheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353886/
https://ncbi.nlm.nih.gov/pubmed/22615895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037071
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