Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart

AIMS: Cardiolipin (CL) is a tetra-acyl phospholipid that provides structural and functional support to several proteins in the inner mitochondrial membrane. The majority of CL in the healthy mammalian heart contains four linoleic acid acyl chains (L(4)CL). A selective loss of L(4)CL is associated wi...

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Autori principali: Mulligan, Christopher M., Sparagna, Genevieve C., Le, Catherine H., De Mooy, Anthony B., Routh, Melissa A., Holmes, Michael G., Hickson-Bick, Diane L., Zarini, Simona, Murphy, Robert C., Xu, Fred Y., Hatch, Grant M., McCune, Sylvia A., Moore, Russell L., Chicco, Adam J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2012
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Original Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353802/
https://ncbi.nlm.nih.gov/pubmed/22411972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs118
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