Dietary linoleate preserves cardiolipin and attenuates mitochondrial dysfunction in the failing rat heart

AIMS: Cardiolipin (CL) is a tetra-acyl phospholipid that provides structural and functional support to several proteins in the inner mitochondrial membrane. The majority of CL in the healthy mammalian heart contains four linoleic acid acyl chains (L(4)CL). A selective loss of L(4)CL is associated wi...

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Detalhes bibliográficos
Main Authors: Mulligan, Christopher M., Sparagna, Genevieve C., Le, Catherine H., De Mooy, Anthony B., Routh, Melissa A., Holmes, Michael G., Hickson-Bick, Diane L., Zarini, Simona, Murphy, Robert C., Xu, Fred Y., Hatch, Grant M., McCune, Sylvia A., Moore, Russell L., Chicco, Adam J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353802/
https://ncbi.nlm.nih.gov/pubmed/22411972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvs118
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