Combination Epigenetic Therapy Has Efficacy in Patients with Refractory Advanced Non Small Cell Lung Cancer

Epigenetic alterations are strongly associated with cancer development. We conducted a phase I/II trial of combined epigenetic therapy with azacitidine and entinostat, inhibitors of DNA methylation and histone deacetylation, respectively, in extensively pretreated patients with recurrent metastatic...

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Xehetasun bibliografikoak
Egile Nagusiak: Juergens, Rosalyn A., Wrangle, John, Vendetti, Frank P., Murphy, Sara C., Zhao, Ming, Coleman, Barbara, Sebree, Rosa, Rodgers, Kristen, Hooker, Craig M., Franco, Noreli, Lee, Beverly, Tsai, Salina, Delgado, Igor Espinoza, Rudek, Michelle A., Belinsky, Steven A., Herman, James G., Baylin, Stephen B., Brock, Malcolm V., Rudin, Charles M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353724/
https://ncbi.nlm.nih.gov/pubmed/22586682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-11-0214
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