HJURP uses distinct CENP-A surfaces to recognize and to stabilize CENP-A/histone H4 for centromere assembly

Centromeres are defined by the presence of chromatin containing the histone H3 variant, CENP-A, whose assembly into nucleosomes requires the chromatin assembly factor HJURP. We find that while surface-exposed residues in the CENP-A targeting domain (CATD) are the primary sequence determinants for HJ...

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Autors principals: Bassett, Emily A., DeNizio, Jamie, Barnhart-Dailey, Meghan C., Panchenko, Tanya, Sekulic, Nikolina, Rogers, Danielle J., Foltz, Daniel R., Black, Ben E.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353549/
https://ncbi.nlm.nih.gov/pubmed/22406139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.02.001
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