Anti-tumor effect of 5-aza-2'-deoxycytidine by inhibiting telomerase activity in hepatocellular carcinoma cells

AIM: To investigate the effect of the demethylating reagent 5-aza-2’-deoxycitidine (DAC) on telomerase activity in hepatocellular carcinoma (HCC) cell lines, SMMC-7721 and HepG2. METHODS: The related gene expression in cell lines was examined by real-time reverse transcription-polymerase chain react...

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Autors principals: Tao, Shuang-Fen, Zhang, Chang-Song, Guo, Xian-Ling, Xu, Yun, Zhang, Shan-Shan, Song, Jian-Rui, Li, Rong, Wu, Meng-Chao, Wei, Li-Xin
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2012
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353367/
https://ncbi.nlm.nih.gov/pubmed/22654424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v18.i19.2334
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