Genetic deletion of dectin-1 does not affect the course of murine experimental colitis

BACKGROUND: It is believed that inflammatory bowel diseases (IBD) result from an imbalance in the intestinal immune response towards the luminal microbiome. Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewi...

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Autors principals: Heinsbroek, Sigrid EM, Oei, Anneke, Roelofs, Joris JTH, Dhawan, Shobhit, te Velde, Anje, Gordon, Siamon, de Jonge, Wouter J
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353241/
https://ncbi.nlm.nih.gov/pubmed/22507600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-230X-12-33
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