Long Lifetime of Hydrogen-Bonded DNA Basepairs by Force Spectroscopy

Electron-tunneling data suggest that a noncovalently-bonded complex of three molecules, two recognition molecules that present hydrogen-bond donor and acceptor sites via a carboxamide group, and a DNA base, remains bound for seconds. This is surprising, given that imino-proton exchange rates show th...

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Autors principals: Fuhrmann, Alexander, Getfert, Sebastian, Fu, Qiang, Reimann, Peter, Lindsay, Stuart, Ros, Robert
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Spectroscopy, Imaging, and Other Techniques
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3353008/
https://ncbi.nlm.nih.gov/pubmed/22677392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.006
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