Identification of phosphate groups important to self-splicing of the Tetrahymena rRNA intron as determined by phosphorothioate substitution.
The group I intron from the rRNA precursor of Tetrahymena undergoes self-splicing. The intron RNA catalyst contains about 400 phosphate groups. Their role in catalysis has been investigated using phosphorothioate substituted RNA. In such RNA one of the peripheral oxygens of the phosphodiesters is re...
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| Veröffentlicht in: | Nucleic Acids Res |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1989
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| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2690016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/17.24.10281 |
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