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Hydroxyl radical "footprinting" of RNA: application to pre-mRNA splicing complexes.

We present an adaptation of the hydroxyl radical DNA "footprinting" technique that permits high-resolution mapping of protected regions of RNA. Hydroxyl radical cleaves RNA independently of base sequence and secondary structure of the RNAs examined and allows resolution of protected region...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wang, X D, Padgett, R A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.7795
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