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Hydroxyl radical "footprinting" of RNA: application to pre-mRNA splicing complexes.

We present an adaptation of the hydroxyl radical DNA "footprinting" technique that permits high-resolution mapping of protected regions of RNA. Hydroxyl radical cleaves RNA independently of base sequence and secondary structure of the RNAs examined and allows resolution of protected regions at the s...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Wang, X D, Padgett, R A
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298157/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2554290/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.20.7795
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