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Mechanisms of the proteinuria induced by Rho GTPases

Podocytes are highly differentiated cells that play an important role in maintaining glomerular filtration barrier integrity; a function regulated by small GTPase proteins of the Rho family. To investigate the role of Rho A in podocyte biology, we created transgenic mice expressing doxycycline-induc...

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Autores principales: Wang, Liming, Ellis, Mathew J., Gomez, Jose A., Eisner, William, Fennell, Walter, Howell, David N., Ruiz, Phillip, Fields, Timothy A., Spurney, Robert F.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352980/
https://ncbi.nlm.nih.gov/pubmed/22278020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.472
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