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Hyperphosphorylation and Cleavage at D421 Enhance Tau Secretion
It is well established that tau pathology propagates in a predictable manner in Alzheimer’s disease (AD). Moreover, tau accumulates in the cerebrospinal fluid (CSF) of AD’s patients. The mechanisms underlying the propagation of tau pathology and its accumulation in the CSF remain to be elucidated. R...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3352936/ https://ncbi.nlm.nih.gov/pubmed/22615831 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0036873 |
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