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Biodistribution and pharmacokinetics of a telodendrimer micellar paclitaxel nanoformulation in a mouse xenograft model of ovarian cancer

BACKGROUND: A multifunctional telodendrimer-based micelle system was characterized for delivery of imaging and chemotherapy agents to mouse tumor xenografts. Previous optical imaging studies demonstrated qualitatively that these classes of nanoparticles, called nanomicelles, preferentially accumulat...

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Detalhes bibliográficos
Main Authors: Xiao, Wenwu, Luo, Juntao, Jain, Teesta, Riggs, John W, Tseng, Harry P, Henderson, Paul T, Cherry, Simon R, Rowland, Douglas, Lam, Kit S
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352867/
https://ncbi.nlm.nih.gov/pubmed/22605931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S29306
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