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Mechanisms and Evolutionary Patterns of Mammalian and Avian Dosage Compensation
As a result of sex chromosome differentiation from ancestral autosomes, male mammalian cells only contain one X chromosome. It has long been hypothesized that X-linked gene expression levels have become doubled in males to restore the original transcriptional output, and that the resulting X overexp...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3352821/ https://ncbi.nlm.nih.gov/pubmed/22615540 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001328 |
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