Uptake and transport of a novel anticancer drug-delivery system: lactosyl-norcantharidin-associated N-trimethyl chitosan nanoparticles across intestinal Caco-2 cell monolayers

In this paper, novel liver-targeting nanoparticles (NPs), lactosyl-norcantharidin (Lac-NCTD)-associated N-trimethyl chitosan (TMC) NPs (Lac-NCTD-TMC-NPs), were prepared using ionic cross-linkage. The physical properties, particle size, and encapsulation efficiency of the nanoparticles were then inve...

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Bibliografske podrobnosti
Main Authors: Guan, Min, Zhu, Qiao-Ling, Liu, Yang, Bei, Yong-Yan, Gu, Zong-Lin, Zhang, Xue-Nong, Zhang, Qiang
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2012
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352694/
https://ncbi.nlm.nih.gov/pubmed/22605938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S30034
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