The KL-VS sequence variant of Klotho and cancer risk in BRCA1 and BRCA2 mutation carriers

Klotho (KL) is a putative tumor suppressor gene in breast and pancreatic cancers located at chromosome 13q12. A functional sequence variant of Klotho (KL-VS) was previously reported to modify breast cancer risk in Jewish BRCA1 mutation carriers. The effect of this variant on breast and ovarian cance...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Laitman, Yael, Kuchenbaecker, Karoline B., Rantala, Johanna, Hogervorst, Frans, Peock, Susan, Godwin, Andrew K., Arason, Adalgeir, Kirchhoff, Tomas, Offit, Kenneth, Isaacs, Claudine, Schmutzler, Rita K., Wappenschmidt, Barbara, Nevanlinna, Heli, Chen, Xiaoqing, Chenevix-Trench, Georgia, Healey, Sue, Couch, Fergus, Peterlongo, Paolo, Radice, Paolo, Nathanson, Katherine L., Caligo, Maria Adelaide, Neuhausen, Susan L., Ganz, Patricia, Sinilnikova, Olga M., McGuffog, Lesley, Easton, Douglas F., Antoniou, Antonis C., Wolf, Ido, Friedman, Eitan
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352679/
https://ncbi.nlm.nih.gov/pubmed/22212556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-011-1938-8
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi