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Production of baculovirus defective interfering particles during serial passage is delayed by removing transposon target sites in fp25k
Accumulation of baculovirus defective interfering particle (DIP) and few polyhedra (FP) mutants is a major limitation to continuous large-scale baculovirus production in insect-cell culture. Although overcoming these mutations would result in a cheaper platform for producing baculovirus biopesticide...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Society for General Microbiology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3352349/ https://ncbi.nlm.nih.gov/pubmed/21994323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.036566-0 |
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