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Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98

Human cytomegalovirus encodes an alkaline nuclease, UL98, that is highly conserved among herpesviruses and has both endonuclease (endo) and exonuclease (exo) activities. This protein is thought to be important for viral replication and therefore represents a potential target for antiviral developmen...

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書誌詳細
主要な著者: Kuchta, Alison L., Parikh, Hardik, Zhu, Yali, Kellogg, Glen E., Parris, Deborah S., McVoy, Michael A.
フォーマット: Artigo
言語:Inglês
出版事項: Society for General Microbiology 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352332/
https://ncbi.nlm.nih.gov/pubmed/21900421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.034876-0
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