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Structural modelling and mutagenesis of human cytomegalovirus alkaline nuclease UL98

Human cytomegalovirus encodes an alkaline nuclease, UL98, that is highly conserved among herpesviruses and has both endonuclease (endo) and exonuclease (exo) activities. This protein is thought to be important for viral replication and therefore represents a potential target for antiviral developmen...

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Autori principali: Kuchta, Alison L., Parikh, Hardik, Zhu, Yali, Kellogg, Glen E., Parris, Deborah S., McVoy, Michael A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for General Microbiology 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352332/
https://ncbi.nlm.nih.gov/pubmed/21900421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.034876-0
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