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Drugs developed to treat diabetes, liraglutide and lixisenatide, cross the blood brain barrier and enhance neurogenesis

BACKGROUND: Type 2 diabetes is a risk factor for Alzheimer's disease (AD), most likely linked to an impairment of insulin signalling in the brain. Therefore, drugs that enhance insulin signalling may have therapeutic potential for AD. Liraglutide (Victoza) and exenatide (Byetta) are novel long-...

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Detalhes bibliográficos
Main Authors: Hunter, Kerry, Hölscher, Christian
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352246/
https://ncbi.nlm.nih.gov/pubmed/22443187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2202-13-33
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