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Loss of Heterozygosity at the Glutathione Peroxidase 1 Locus Is Not an Early Event in Colon Carcinogenesis

It has been previously shown that loss of heterozygosity (LOH) at the cytosolic glutathione peroxidase (GPx-1) locus is a common event in the development of several cancer types, including colorectal cancer. GPx-1 is an antioxidant selenium-containing protein, and polymorphisms within this gene have...

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Detalhes bibliográficos
Main Authors: Goldberg, Marci, Alberts, David S., Buckmeier, Julie A., Prasad, Anil R., Krouse, Robert S., Diamond, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE Publications 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3352152/
https://ncbi.nlm.nih.gov/pubmed/22593803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1947601911431840
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