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Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans
Cholesterol regulates the signaling of µ-opioid receptor in cell models, but it has not been demonstrated in mice or humans. Whether cholesterol regulates the signaling by mechanisms other than supporting the entirety of lipid raft microdomains is still unknown. By modulating cholesterol-enriched li...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351822/ https://ncbi.nlm.nih.gov/pubmed/22377533 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024455 |
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