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Cholesterol level influences opioid signaling in cell models and analgesia in mice and humans

Cholesterol regulates the signaling of µ-opioid receptor in cell models, but it has not been demonstrated in mice or humans. Whether cholesterol regulates the signaling by mechanisms other than supporting the entirety of lipid raft microdomains is still unknown. By modulating cholesterol-enriched li...

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Detalhes bibliográficos
Main Authors: Zheng, Hui, Zou, Haibo, Liu, Xiaopeng, Chu, Ji, Zhou, Yali, Loh, Horace H., Law, Ping-Yee
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351822/
https://ncbi.nlm.nih.gov/pubmed/22377533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M024455
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