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Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamn D(3) and is required for optimal cell differentiation
Induction of terminal differentiation of neoplastic cells offers potential for a novel approach to cancer therapy. One of the agents being investigated for this purpose in preclinical studies is 1,25-dihydroxyvitamin D(3) (1,25D), which can convert myeloid leukemia cells into normal monocyte-like ce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2007
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351793/ https://ncbi.nlm.nih.gov/pubmed/17599832 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2007.05.021 |
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