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Raf-1 Signaling Is Required for the Later Stages of 1,25-Dihydroxyvitamin D(3)-Induced Differentiation of HL60 Cells But Is Not Mediated by the MEK/ERK Module

We are interested in determining the signaling pathways for 1,25-dihydroxyvitamin D(3) (1,25D)-induced differentiation of HL60 leukemic cells. One possible candidate is Raf-1, which is known to signal cell proliferation and neoplastic transformation through MEK, ERK, and downstream targets. It can a...

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Autors principals: Wang, Xuening, Studzinski, George P.
Format: Artigo
Idioma:Inglês
Publicat: 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2814417/
https://ncbi.nlm.nih.gov/pubmed/16883571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.20731
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