Accurate Localization and Relative Quantification of Arginine Methylation Using Nanoflow Liquid Chromatography Coupled to Electron Transfer Dissociation and Orbitrap Mass Spectrometry

Protein arginine (Arg) methylation serves an important functional role in eukaryotic cells, and typically occurs in domains consisting of multiple Arg in close proximity. Localization of methylarginine (MA) within Arg-rich domains poses a challenge for mass spectrometry (MS)-based methods; the pepti...

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Bibliographic Details
Main Authors: Wang, Hao, Straubinger, Robert M., Aletta, John M., Cao, Jin, Duan, Xiaotao, Yu, Haoying, Qu, Jun
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3351756/
https://ncbi.nlm.nih.gov/pubmed/19110445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2008.11.008
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