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Ultra-sensitive quantification of paclitaxel using selective solid-phase extraction in conjunction with reversed-phase capillary liquid chromatography/tandem mass spectrometry

The ability to quantify ultra-low concentrations of biologically active compounds in biological matrices is essential for the study of pharmacological/toxicological effects occurring at low doses. Selective solid-phase extraction (SPE) was combined with highly sensitive capillary LC (μLC)-MS/MS anal...

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Detalhes bibliográficos
Main Authors: Yu, Haoying, Straubinger, Robert M., Cao, Jin, Wang, Hao, Qu, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586302/
https://ncbi.nlm.nih.gov/pubmed/18834593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chroma.2008.09.052
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