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Transgene expression and local tissue distribution of naked and polymer-condensed plasmid DNA after intradermal administration in mice
DNA vaccination using cationic polymers as carriers has the potential to be a very powerful method of immunotherapy, but typical immune responses generated have been less than robust. To better understand the details of DNA vaccine delivery in vivo, we prepared polymer/DNA complexes using three stru...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3351500/ https://ncbi.nlm.nih.gov/pubmed/22300619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.01.012 |
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