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Block Copolymer Micelles with Acid-labile Ortho Ester Side-chains: Synthesis, Characterization, and Enhanced Drug Delivery to Human Glioma Cells

A new type of block copolymer micelles for pH-triggered delivery of poorly water-soluble anticancer drugs has been synthesized and characterized. The micelles were formed by the self-assembly of an amphiphilic diblock copolymer consisting of a hydrophilic poly(ethylene glycol) (PEG) block and a hydr...

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Détails bibliographiques
Auteurs principaux: Tang, Rupei, Ji, Weihang, Panus, David, Palumbo, R. Noelle, Wang, Chun
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3081958/
https://ncbi.nlm.nih.gov/pubmed/21194551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.12.005
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